Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations

Interleukin 15 (IL-15), a four-helix bundle cytokine, is involved in a plethora of different cellular functions and, particularly, plays a key role in the development and activation of immune responses. IL-15 forms receptor complexes by binding with IL-2Rβ- and common γ (γc)-signaling subunits, whic...

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Detalles Bibliográficos
Autores principales: Sousa, Rui P., Laurent, Adèle D., Quéméner, Agnès, Mortier, Erwan, Le Questel, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767322/
https://www.ncbi.nlm.nih.gov/pubmed/31500206
http://dx.doi.org/10.3390/molecules24183261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767322/
https://www.ncbi.nlm.nih.gov/pubmed/31500206
http://dx.doi.org/10.3390/molecules24183261

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