High‐throughput single‐cell sequencing of paired TCRα and TCRβ genes for the direct expression‐cloning and functional analysis of murine T‐cell receptors

Precise clonal and functional assessments of the T cell receptor (TCR) repertoire diversity require paired TCRα and TCRβ gene sequence information at monoclonal level. However, available single‐cell strategies are typically limited in throughput and often do not provide full‐length DNA templates for...

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Detalles Bibliográficos
Autores principales: Ludwig, Julia, Huber, Ann‐Kathrin, Bartsch, Ilka, Busse, Christian E., Wardemann, Hedda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
New technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767390/
https://www.ncbi.nlm.nih.gov/pubmed/31017295
http://dx.doi.org/10.1002/eji.201848030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767390/
https://www.ncbi.nlm.nih.gov/pubmed/31017295
http://dx.doi.org/10.1002/eji.201848030

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