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Activation of the prostaglandin E(2) EP(2) receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices

AIM: Renal fibrosis plays a pivotal role in the development and progression of chronic kidney disease, which affects 10% of the adult population. Previously, it has been demonstrated that the cyclooxygenase‐2 (COX‐2)/prostaglandin (PG) system influences the progression of renal injury. Here, we eval...

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Detalles Bibliográficos
Autores principales: Jensen, Michael Schou, Mutsaers, Henricus A. M., Tingskov, Stine Julie, Christensen, Michael, Madsen, Mia Gebauer, Olinga, Peter, Kwon, Tae‐Hwan, Nørregaard, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767420/
https://www.ncbi.nlm.nih.gov/pubmed/31054202
http://dx.doi.org/10.1111/apha.13291