Oncolytic virotherapy enhances the efficacy of a cancer vaccine by modulating the tumor microenvironment

The efficacy of cancer vaccines has been limited by the immunosuppressive tumor microenvironment, which can be alleviated by immune checkpoint inhibitor (ICI) therapy. Here, we tested if oncolytic viruses (OVs), similar to ICI, can also synergize with cancer vaccines by modulating the tumor microenv...

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Detalles Bibliográficos
Autores principales: Koske, Iris, Rössler, Annika, Pipperger, Lisa, Petersson, Monika, Barnstorf, Isabel, Kimpel, Janine, Tripp, Christoph H., Stoitzner, Patrizia, Bánki, Zoltán, von Laer, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Tumor Immunology and Microenvironment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767478/
https://www.ncbi.nlm.nih.gov/pubmed/30972741
http://dx.doi.org/10.1002/ijc.32325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767478/
https://www.ncbi.nlm.nih.gov/pubmed/30972741
http://dx.doi.org/10.1002/ijc.32325

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