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Oncolytic virotherapy enhances the efficacy of a cancer vaccine by modulating the tumor microenvironment
The efficacy of cancer vaccines has been limited by the immunosuppressive tumor microenvironment, which can be alleviated by immune checkpoint inhibitor (ICI) therapy. Here, we tested if oncolytic viruses (OVs), similar to ICI, can also synergize with cancer vaccines by modulating the tumor microenv...
Autores principales: | Koske, Iris, Rössler, Annika, Pipperger, Lisa, Petersson, Monika, Barnstorf, Isabel, Kimpel, Janine, Tripp, Christoph H., Stoitzner, Patrizia, Bánki, Zoltán, von Laer, Dorothee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767478/ https://www.ncbi.nlm.nih.gov/pubmed/30972741 http://dx.doi.org/10.1002/ijc.32325 |
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