Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration

Disulfiram has been used in the treatment of alcoholism and exhibits an anti-tumor effect. However, the intracellular mechanism of anti-tumor activity of Disulfiram remains unclear. In this study, we focused on the modulatory role of Disulfiram via oncogenic factor carbonic anhydrase CA12 and its as...

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Detalles Bibliográficos
Autores principales: Hwang, Soyoung, Shin, Dong Min, Hong, Jeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767608/
https://www.ncbi.nlm.nih.gov/pubmed/31546841
http://dx.doi.org/10.3390/molecules24183409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767608/
https://www.ncbi.nlm.nih.gov/pubmed/31546841
http://dx.doi.org/10.3390/molecules24183409

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