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Identifying Crohn’s disease signal from variome analysis

BACKGROUND: After years of concentrated research efforts, the exact cause of Crohn’s disease (CD) remains unknown. Its accurate diagnosis, however, helps in management and preventing the onset of disease. Genome-wide association studies have identified 241 CD loci, but these carry small log odds rat...

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Detalles Bibliográficos
Autores principales: Wang, Yanran, Miller, Maximilian, Astrakhan, Yuri, Petersen, Britt-Sabina, Schreiber, Stefan, Franke, Andre, Bromberg, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767648/
https://www.ncbi.nlm.nih.gov/pubmed/31564248
http://dx.doi.org/10.1186/s13073-019-0670-6