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miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer worldwide and is one of the most lethal malignancies. Cisplatin (DDP) is a key drug for ESCC treatment, but the presence of chemotherapy resistance limits the use of DDP. To enhance chemosensitivity to DDP is impo...

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Detalles Bibliográficos
Autores principales: Zheng, Tian-Liang, Li, De-Ping, He, Zhan-Feng, Zhao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767650/
https://www.ncbi.nlm.nih.gov/pubmed/31582906
http://dx.doi.org/10.1186/s12935-019-0943-6