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miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer worldwide and is one of the most lethal malignancies. Cisplatin (DDP) is a key drug for ESCC treatment, but the presence of chemotherapy resistance limits the use of DDP. To enhance chemosensitivity to DDP is impo...

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Detalles Bibliográficos
Autores principales:	Zheng, Tian-Liang, Li, De-Ping, He, Zhan-Feng, Zhao, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767650/ https://www.ncbi.nlm.nih.gov/pubmed/31582906 http://dx.doi.org/10.1186/s12935-019-0943-6

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