A computational model of induced pluripotent stem‐cell derived cardiomyocytes incorporating experimental variability from multiple data sources

KEY POINTS: Induced pluripotent stem cell‐derived cardiomyocytes (iPSC‐CMs) capture patient‐specific genotype–phenotype relationships, as well as cell‐to‐cell variability of cardiac electrical activity. Computational modelling and simulation provide a high throughput approach to reconcile multiple d...

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Detalles Bibliográficos
Autores principales: Kernik, Divya C., Morotti, Stefano, Wu, HaoDi, Garg, Priyanka, Duff, Henry J., Kurokawa, Junko, Jalife, José, Wu, Joseph C., Grandi, Eleonora, Clancy, Colleen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Computational Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767694/
https://www.ncbi.nlm.nih.gov/pubmed/31278749
http://dx.doi.org/10.1113/JP277724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767694/
https://www.ncbi.nlm.nih.gov/pubmed/31278749
http://dx.doi.org/10.1113/JP277724

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