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DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough

BACKGROUND: Extracellular adenosine 5′-triphosphate (ATP) plays important mechanistic roles in pulmonary disorders in general and chronic obstructive pulmonary disease (COPD) and cough in particular. The effects of ATP in the lungs are mediated to a large extent by P2X2/3 receptors (P2X2/3R) localiz...

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Detalles Bibliográficos
Autores principales: Pelleg, Amir, Xu, Fadi, Zhuang, Jianguo, Undem, Bradley, Burnstock, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767719/
https://www.ncbi.nlm.nih.gov/pubmed/31558105
http://dx.doi.org/10.1177/1753466619877960