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DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough
BACKGROUND: Extracellular adenosine 5′-triphosphate (ATP) plays important mechanistic roles in pulmonary disorders in general and chronic obstructive pulmonary disease (COPD) and cough in particular. The effects of ATP in the lungs are mediated to a large extent by P2X2/3 receptors (P2X2/3R) localiz...
Autores principales: | Pelleg, Amir, Xu, Fadi, Zhuang, Jianguo, Undem, Bradley, Burnstock, Geoffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767719/ https://www.ncbi.nlm.nih.gov/pubmed/31558105 http://dx.doi.org/10.1177/1753466619877960 |
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