BZD9L1 sirtuin inhibitor as a potential adjuvant for sensitization of colorectal cancer cells to 5-fluorouracil

BACKGROUND: This study aims to investigate the combination effect of a novel sirtuin inhibitor (BZD9L1) with 5-fluorouracil (5-FU) and to determine its molecular mechanism of action in colorectal cancer (CRC). METHODS: BZD9L1 and 5-FU either as single treatment or in combination were tested against...

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Detalles Bibliográficos
Autores principales: Tan, Yi Jer, Lee, Yeuan Ting, Petersen, Sven H., Kaur, Gurjeet, Kono, Koji, Tan, Soo Choon, Majid, Amin M. S. Abdul, Oon, Chern Ein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767736/
https://www.ncbi.nlm.nih.gov/pubmed/31632470
http://dx.doi.org/10.1177/1758835919878977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767736/
https://www.ncbi.nlm.nih.gov/pubmed/31632470
http://dx.doi.org/10.1177/1758835919878977

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