Cargando…

Novel multi-drugs incorporating hybrid-structured nanofibers enhance alkylating agent activity in malignant gliomas

BACKGROUND: Malignant gliomas (MGs) are highly chemotherapy-resistant. Temozolomide (TMZ) and carmustine (BiCNU) are alkylating agents clinically used for treating MGs. However, their effectiveness is restrained by overexpression of the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Shih-Jung, Yang, Shun-Tai, Chen, Shu-Mei, Huang, Yin-Chen, Lee, Wei-Hwa, Ho, Jui, Chen, Yin-Chun, Tseng, Yuan-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767748/ https://www.ncbi.nlm.nih.gov/pubmed/31632467 http://dx.doi.org/10.1177/1758835919875555

Ejemplares similares

Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes
por: Tseng, Yuan-Yun, et al.
Publicado: (2016)

Injectable SN-38-embedded Polymeric Microparticles Promote Antitumor Efficacy against Malignant Glioma in an Animal Model
por: Tseng, Yuan-Yun, et al.
Publicado: (2020)

Concurrent Chemotherapy of Malignant Glioma in Rats by Using Multidrug-Loaded Biodegradable Nanofibrous Membranes
por: Tseng, Yuan-Yun, et al.
Publicado: (2016)

Evaluation of a Hydrophobic Coating Agent Based on Cellulose Nanofiber and Alkyl Ketone Dimer
por: Jang, Nag-Seop, et al.
Publicado: (2023)

Role of Polymeric Local Drug Delivery in Multimodal Treatment of Malignant Glioma: A Review
por: Tseng, Yuan-Yun, et al.
Publicado: (2021)

Increased therapeutic efficiency of a lipid-soluble alkylating agent incorporated in liposomes.
por: Babbage, J. W., et al.
Publicado: (1982)

Glioma Cell Death Induced by Irradiation or Alkylating Agent Chemotherapy Is Independent of the Intrinsic Ceramide Pathway
por: Gramatzki, Dorothee, et al.
Publicado: (2013)

Enzyme activated alkylating agents.
por: Ball, C. R., et al.
Publicado: (1973)

Synthesis and Biological Evaluation of Novel 1-Alkyl-tryptophan Analogs as Potential Antitumor Agents
por: Sun, Ting, et al.
Publicado: (2009)

Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents
por: Silva, Simone Rodrigues, et al.
Publicado: (2015)

Sustained Release of Antifungal and Antibacterial Agents from Novel Hybrid Degradable Nanofibers for the Treatment of Polymicrobial Osteomyelitis
por: Hsu, Yung-Heng, et al.
Publicado: (2023)

Drug Repurposing of Metabolic Agents in Malignant Glioma
por: Seliger, Corinna, et al.
Publicado: (2018)

Anesthetics and human epidermal growth factor incorporated into anti-adhesive nanofibers provide sustained pain relief and promote healing of surgical wounds
por: Kao, Ching-Wei, et al.
Publicado: (2019)

Novel Biodegradable 3D-Printed Analgesics-Eluting-Nanofibers Incorporated Nuss Bars for Therapy of Pectus Excavatum
por: Liu, Kuo-Sheng, et al.
Publicado: (2022)

Ligand-enabled Ni-catalysed enantioconvergent intermolecular Alkyl-Alkyl cross-coupling between distinct Alkyl halides
por: Zhao, Wen-Tao, et al.
Publicado: (2023)

Proceedings: Alkylating agents as industrial carcinogens.
por: Munn, A.
Publicado: (1975)

Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response
por: Chu, Pei-Ming, et al.
Publicado: (2011)

Assessing the Efficacy of Alkylating Agent Regimens in the Treatment of Infantile Malignant Osteopetrosis: Cyclophosphamide, Busulfan, or Thiotepa
por: Wagh, Himanshu, et al.
Publicado: (2022)

O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
por: Bobola, Michael S., et al.
Publicado: (2014)

Polydatin Incorporated in Polycaprolactone Nanofibers Improves Osteogenic Differentiation
por: Lama, Stefania, et al.
Publicado: (2022)

Nickel-catalyzed migratory alkyl–alkyl cross-coupling reaction
por: Li, Yangyang, et al.
Publicado: (2020)

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes
por: Tran, Thai Q., et al.
Publicado: (2017)

Incorporation of functionalized gold nanoparticles into nanofibers for enhanced attachment and differentiation of mammalian cells
por: Jung, Dongju, et al.
Publicado: (2012)

Improving the therapeutic index of two alkylating agents.
por: Millar, J. L., et al.
Publicado: (1980)

Ablation of murine jejunal crypts by alkylating agents.
por: Moore, J. V.
Publicado: (1979)

Urinary markers for exposures to alkylating or nitrosating agents.
por: Wishnok, J S, et al.
Publicado: (1993)

Temozolomide and Other Alkylating Agents in Glioblastoma Therapy
por: Strobel, Hannah, et al.
Publicado: (2019)

Alkylating anticancer agents and their relations to microRNAs
por: Biersack, Bernhard
Publicado: (2019)

Radially patterned polycaprolactone nanofibers as an active wound dressing agent
por: Shin, Dongwoo, et al.
Publicado: (2019)

Combining molecular targeted agents with radiation therapy for malignant gliomas
por: Scaringi, Claudia, et al.
Publicado: (2013)

Quercetin-gold nanorods incorporated into nanofibers: development, optimization and cytotoxicity
por: Mahmoud, Nouf N., et al.
Publicado: (2021)

Incorporation of Mycobacteriophage Fulbright into Polycaprolactone Electrospun Nanofiber Wound Dressing
por: Kotturi, Hari, et al.
Publicado: (2022)

Incorporation and Deposition of Spin Crossover Materials into and onto Electrospun Nanofibers
por: Kilic, Maximilian Seydi, et al.
Publicado: (2023)

Biomedical Applications of Magnetically Functionalized Organic/Inorganic Hybrid Nanofibers
por: Lee, Hwa-Jeong, et al.
Publicado: (2015)

Enhancement of Electromagnetic Wave Shielding Effectiveness by the Incorporation of Carbon Nanofibers–Carbon Microcoils Hybrid into Commercial Carbon Paste for Heating Films
por: Kang, Gi-Hwan, et al.
Publicado: (2023)

Incorporation of Perillyl Alcohol into Lipid-Based Nanocarriers Enhances the Antiproliferative Activity in Malignant Glioma Cells
por: Ahmed, Tarek A., et al.
Publicado: (2023)

Alkylboronic acids as alkylating agents: photoredox-catalyzed alkylation reactions assisted by K(3)PO(4)
por: Yue, Fuyang, et al.
Publicado: (2022)

PQQ Dietary Supplementation Prevents Alkylating Agent-Induced Ovarian Dysfunction in Mice
por: Dai, Xiuliang, et al.
Publicado: (2022)

DNA Damage Induced by Alkylating Agents and Repair Pathways
por: Kondo, Natsuko, et al.
Publicado: (2010)

Alcohols as alkylating agents in heteroarene C–H functionalization
por: Jin, Jian, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_17qcti0dbf6e5hi9l13a52tch2