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Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B*13:01

BACKGROUND: Research into drug hypersensitivity associated with the expression of specific HLA alleles has focussed on the interaction between parent drug and the HLA with no attention given to reactive metabolites. For this reason, we have studied HLA‐B*13:01‐linked dapsone hypersensitivity to (a)...

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Detalles Bibliográficos
Autores principales: Zhao, Qing, Alhilali, Khetam, Alzahrani, Abdulaziz, Almutairi, Mubarak, Amjad, Juwaria, Liu, Hong, Sun, Yonghu, Sun, Lele, Zhang, Huimin, Meng, Xiaoli, Gibson, Andrew, Ogese, Monday O., Kevin Park, B., Liu, Jianjun, Ostrov, David A., Zhang, Furen, Naisbitt, Dean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767778/
https://www.ncbi.nlm.nih.gov/pubmed/30844087
http://dx.doi.org/10.1111/all.13769