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(-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice

Traumatic brain injury (TBI), a major cause of mortality and morbidity, affects 10 million people worldwide, with limited treatment options. We have previously shown that (-)-phenserine (Phen), an acetylcholinesterase inhibitor originally designed and tested in clinical phase III trials for Alzheime...

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Detalles Bibliográficos
Autores principales: Hsueh, Shih-Chang, Lecca, Daniela, Greig, Nigel H., Wang, Jia-Yi, Selman, Warren, Hoffer, Barry J., Miller, Jonathan P., Chiang, Yung-Hsiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767878/
https://www.ncbi.nlm.nih.gov/pubmed/31177840
http://dx.doi.org/10.1177/0963689719854693