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High mobility group box-1 release from H(2)O(2)-injured hepatocytes due to sirt1 functional inhibition

BACKGROUND: High mobility group box-1 (HMGB1), recognized as a representative of damage-associated molecular patterns, is released during cell injury/death, triggering the inflammatory response and ultimately resulting in tissue damage. Dozens of studies have shown that HMGB1 is involved in certain...

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Detalles Bibliográficos
Autores principales: Ye, Ting-Jie, Lu, Yan-Lin, Yan, Xiao-Feng, Hu, Xu-Dong, Wang, Xiao-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767985/
https://www.ncbi.nlm.nih.gov/pubmed/31576091
http://dx.doi.org/10.3748/wjg.v25.i36.5434