Development of a practical synthesis of etravirine via a microwave-promoted amination

BACKGROUND: Etravirine (ETV) was approved as the second generation drug for use in individuals infected with HIV-1 in 2008 by the U.S. FDA with its unique antiviral activity, high specificity, and low toxicity. However, there are some shortcomings of the existing synthetic routes, such as the long r...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Da, Wei, Fenju, Wang, Zhao, Kang, Dongwei, Zhan, Peng, Liu, Xinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768033/
https://www.ncbi.nlm.nih.gov/pubmed/30569261
http://dx.doi.org/10.1186/s13065-018-0504-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768033/
https://www.ncbi.nlm.nih.gov/pubmed/30569261
http://dx.doi.org/10.1186/s13065-018-0504-4

Ejemplares similares