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Hybrid caffeic acid derivatives as monoamine oxidases inhibitors: synthesis, radical scavenging activity, molecular docking studies and in silico ADMET analysis

BACKGROUND: Monoamine oxidase has been implicated in numerous neurological disorders. Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with many side effects, the aspiration of natural based MAOI has greatly increased. As they exhibit fewer side effects and food interaction along...

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Detalles Bibliográficos
Autores principales: Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768041/
https://www.ncbi.nlm.nih.gov/pubmed/30413989
http://dx.doi.org/10.1186/s13065-018-0481-7