Protection from Endotoxin Shock by Selective Targeting of Proinflammatory Signaling to the Nucleus Mediated by Importin Alpha 5

Endotoxin shock is induced by LPS, one of the most potent virulence factors of the Gram-negative bacteria that cause sepsis. It remains unknown if either proinflammatory stress-responsive transcription factors (SRTFs), ferried to nucleus by importin α5, or lipid-regulating sterol regulatory element...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Veach, Ruth Ann, Zienkiewicz, Jozef, Boyd, Kelli L., Smith, Taylor E., Xu, Zhi-Qi, Wylezinski, Lukasz S., Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768080/
https://www.ncbi.nlm.nih.gov/pubmed/31533951
http://dx.doi.org/10.4049/immunohorizons.1900064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768080/
https://www.ncbi.nlm.nih.gov/pubmed/31533951
http://dx.doi.org/10.4049/immunohorizons.1900064

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