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LKB1 suppresses androgen synthesis in a mouse model of hyperandrogenism via IGF‐1 signaling

Polycystic ovary syndrome (PCOS) is a major cause of anovulatory sterility in women, and most PCOS patients exhibit hyperandrogenism (HA). Liver kinase b1 (LKB1) is a tumor suppressor that has recently been reported to be involved in PCOS. However, the mechanism by which LKB1 affects HA has not prev...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Gao, Yongxing, Huang, Zufang, Zheng, Yan, Teng, Wenjuan, Zheng, Deyan, Zheng, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768104/
https://www.ncbi.nlm.nih.gov/pubmed/31433577
http://dx.doi.org/10.1002/2211-5463.12723