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DNA hypermethylation of Fgf16 and Tbx22 associated with cleft palate during palatal fusion

OBJECTIVE: Cleft palate (CP) is a congenital birth defect caused by the failure of palatal fusion. Little is known about the potential role of DNA methylation in the pathogenesis of CP. This study aimed to explore the potential role of DNA methylation in the mechanism of CP. METHODOLOGY: We establis...

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Detalles Bibliográficos
Autores principales: Shu, Xuan, Dong, Zejun, Cheng, Liuhanghang, Shu, Shenyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768118/
https://www.ncbi.nlm.nih.gov/pubmed/31596367
http://dx.doi.org/10.1590/1678-7757-2018-0649