Design, Synthesis, And Evaluation Of Cyanopyridines As Anti-Colorectal Cancer Agents Via Inhibiting STAT3 Pathway

BACKGROUND: Colorectal cancer is one of the common malignant tumors. Cyanopyridine and aminocyanopyridine having a carbon-nitrogen bond have been shown to have significant anticancer effects. STAT3 is a promising therapeutic target in multiple cancers. However, there are currently no effective STAT3...

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Detalles Bibliográficos
Autores principales: Xu, Lingyuan, Shi, Lingxi, Qiu, Sensen, Chen, Siyu, Lin, Mengsha, Xiang, Youqun, Zhao, Chengguang, Zhu, Jiandong, Shen, Liqun, Zuo, Zhigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768128/
https://www.ncbi.nlm.nih.gov/pubmed/31576111
http://dx.doi.org/10.2147/DDDT.S217800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768128/
https://www.ncbi.nlm.nih.gov/pubmed/31576111
http://dx.doi.org/10.2147/DDDT.S217800

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