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Design, Synthesis, And Evaluation Of Cyanopyridines As Anti-Colorectal Cancer Agents Via Inhibiting STAT3 Pathway

BACKGROUND: Colorectal cancer is one of the common malignant tumors. Cyanopyridine and aminocyanopyridine having a carbon-nitrogen bond have been shown to have significant anticancer effects. STAT3 is a promising therapeutic target in multiple cancers. However, there are currently no effective STAT3...

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Detalles Bibliográficos
Autores principales:	Xu, Lingyuan, Shi, Lingxi, Qiu, Sensen, Chen, Siyu, Lin, Mengsha, Xiang, Youqun, Zhao, Chengguang, Zhu, Jiandong, Shen, Liqun, Zuo, Zhigui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768128/ https://www.ncbi.nlm.nih.gov/pubmed/31576111 http://dx.doi.org/10.2147/DDDT.S217800

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