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Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies

BACKGROUND: An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In this context, herein, we have made an attempt to develop some novel glitazones...

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Detalles Bibliográficos
Autores principales: Mandal, Subhankar P., Garg, Aakriti, Prabitha, P., Wadhwani, Ashish D., Adhikary, Laxmi, Kumar, B. R. Prashantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768137/
https://www.ncbi.nlm.nih.gov/pubmed/30569323
http://dx.doi.org/10.1186/s13065-018-0508-0