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KD025 (SLx-2119) suppresses adipogenesis at intermediate stage in human adipose-derived stem cells

Rho-associated kinases (ROCKs) have been reported to antagonize adipocyte differentiation, and inhibition of ROCKs by small molecules promotes adipogenesis. Surprisingly, our recent study revealed that the ROCK2-specific inhibitor KD025 (SLx-2119), suppresses differentiation at the intermediate stag...

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Detalles Bibliográficos
Autores principales: Diep, Duy Trong Vien, Duong, Khue Ha Minh, Choi, Hojung, Jun, Hee-Sook, Chun, Kwang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768280/
https://www.ncbi.nlm.nih.gov/pubmed/30860936
http://dx.doi.org/10.1080/21623945.2019.1590929