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“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance
BACKGROUND: Pancreatic β-cells adapt to high metabolic demand by expanding their β-cell mass and/or enhancing insulin secretion to maintain glucose homeostasis. Type 2 diabetes (T2D) is typically characterized by β-cell decompensation. SCOPE OF THE REVIEW: The current review focuses on summarizing t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768500/ https://www.ncbi.nlm.nih.gov/pubmed/31500830 http://dx.doi.org/10.1016/j.molmet.2019.06.003 |