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(Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes
BACKGROUND: Pancreatic Islets of Langerhans are heterogeneous tissues consisting of multiple endocrine cell types that carry out distinct yet coordinated roles to regulate blood glucose homeostasis. Islet dysfunction and specifically failure of the beta cells to secrete adequate insulin are known pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768501/ https://www.ncbi.nlm.nih.gov/pubmed/31500827 http://dx.doi.org/10.1016/j.molmet.2019.06.002 |