Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

BACKGROUND: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca(2+)-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; howev...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohara-Imaizumi, Mica, Aoyagi, Kyota, Ohtsuka, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768504/
https://www.ncbi.nlm.nih.gov/pubmed/31500835
http://dx.doi.org/10.1016/j.molmet.2019.06.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768504/
https://www.ncbi.nlm.nih.gov/pubmed/31500835
http://dx.doi.org/10.1016/j.molmet.2019.06.017

Ejemplares similares