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Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

BACKGROUND: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca(2+)-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; howev...

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Detalles Bibliográficos
Autores principales:	Ohara-Imaizumi, Mica, Aoyagi, Kyota, Ohtsuka, Toshihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768504/ https://www.ncbi.nlm.nih.gov/pubmed/31500835 http://dx.doi.org/10.1016/j.molmet.2019.06.017

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