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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy

INTRODUCTION: Vacuolization is a frequently found morphological feature in acute myeloid leukemia (AML) blasts. Subcellular origin and biological function as well as prognostic impact are currently unknown. The aim of this study was to evaluate whether vacuolization correlates with clinically releva...

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Detalles Bibliográficos
Autores principales: Ballo, Olivier, Stratmann, Jan, Serve, Hubert, Steffen, Björn, Finkelmeier, Fabian, Brandts, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768541/
https://www.ncbi.nlm.nih.gov/pubmed/31568521
http://dx.doi.org/10.1371/journal.pone.0223013