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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy
INTRODUCTION: Vacuolization is a frequently found morphological feature in acute myeloid leukemia (AML) blasts. Subcellular origin and biological function as well as prognostic impact are currently unknown. The aim of this study was to evaluate whether vacuolization correlates with clinically releva...
Autores principales: | Ballo, Olivier, Stratmann, Jan, Serve, Hubert, Steffen, Björn, Finkelmeier, Fabian, Brandts, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768541/ https://www.ncbi.nlm.nih.gov/pubmed/31568521 http://dx.doi.org/10.1371/journal.pone.0223013 |
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