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In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells

Nanoparticles in polluted air or aerosolized drug nanoparticles predominantly settle in the alveolar lung. Here, we describe a novel, highly effective pathway for the particles to cross the alveolar epithelium and reach the lymph and bloodstream. Amorphous silica nanoparticles, suspended in perfluor...

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Detalles Bibliográficos
Autores principales: Detampel, Pascal, Ganguly, Anutosh, Tehranian, Sara, Green, Francis, Singha, Santiswarup, Santamaria, Pere, Jeje, Ayodeji A., Cho, Clifford S., Petri, Björn, Amrein, Matthias W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768543/
https://www.ncbi.nlm.nih.gov/pubmed/31568513
http://dx.doi.org/10.1371/journal.pone.0223339