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In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells
Nanoparticles in polluted air or aerosolized drug nanoparticles predominantly settle in the alveolar lung. Here, we describe a novel, highly effective pathway for the particles to cross the alveolar epithelium and reach the lymph and bloodstream. Amorphous silica nanoparticles, suspended in perfluor...
Autores principales: | Detampel, Pascal, Ganguly, Anutosh, Tehranian, Sara, Green, Francis, Singha, Santiswarup, Santamaria, Pere, Jeje, Ayodeji A., Cho, Clifford S., Petri, Björn, Amrein, Matthias W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768543/ https://www.ncbi.nlm.nih.gov/pubmed/31568513 http://dx.doi.org/10.1371/journal.pone.0223339 |
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