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An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis

During mammalian embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis. As effectors of cytoskeletal dynamics, Rho GTPases and their regulators are likely involved, but their daunting complexity has hindered progress in dissecting their functions. We overcome this hurdle by...

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Detalles Bibliográficos
Autores principales: Laurin, Melanie, Gomez, Nicholas C, Levorse, John, Sendoel, Ataman, Sribour, Megan, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768663/
https://www.ncbi.nlm.nih.gov/pubmed/31556874
http://dx.doi.org/10.7554/eLife.50226