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Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia

Preservation of mitochondrial integrity is critical for maintaining cellular homeostasis. Mitophagy is a mitochondria-specific type of autophagy which eliminates damaged mitochondria thereby contributing to mitochondrial quality control. Depolarization of the mitochondrial membrane potential is an e...

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Detalles Bibliográficos
Autores principales: Tan, Valerie P., Smith, Jeffrey M., Tu, Michelle, Yu, Justin D., Ding, Eric Y., Miyamoto, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768853/
https://www.ncbi.nlm.nih.gov/pubmed/31570704
http://dx.doi.org/10.1038/s41419-019-1965-7