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Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia
Preservation of mitochondrial integrity is critical for maintaining cellular homeostasis. Mitophagy is a mitochondria-specific type of autophagy which eliminates damaged mitochondria thereby contributing to mitochondrial quality control. Depolarization of the mitochondrial membrane potential is an e...
Autores principales: | Tan, Valerie P., Smith, Jeffrey M., Tu, Michelle, Yu, Justin D., Ding, Eric Y., Miyamoto, Shigeki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768853/ https://www.ncbi.nlm.nih.gov/pubmed/31570704 http://dx.doi.org/10.1038/s41419-019-1965-7 |
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