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Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer

Prostate cancer (PC) castration resistance has been linked to the differentiation of PC luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular mechanisms controlling the emergence of lethal NE prostate cancer (NEPC) remain unclear. The present study aimed to investig...

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Detalles Bibliográficos
Autores principales: Shan, Jingxuan, Al-Muftah, Mariam A., Al-Kowari, Moza K., Abuaqel, Sirin W. J., Al-Rumaihi, Khalid, Al-Bozom, Issam, Li, Pu, Chouchane, Lotfi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768854/
https://www.ncbi.nlm.nih.gov/pubmed/31583122
http://dx.doi.org/10.1038/s41420-019-0218-y