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Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer
Prostate cancer (PC) castration resistance has been linked to the differentiation of PC luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular mechanisms controlling the emergence of lethal NE prostate cancer (NEPC) remain unclear. The present study aimed to investig...
Autores principales: | Shan, Jingxuan, Al-Muftah, Mariam A., Al-Kowari, Moza K., Abuaqel, Sirin W. J., Al-Rumaihi, Khalid, Al-Bozom, Issam, Li, Pu, Chouchane, Lotfi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768854/ https://www.ncbi.nlm.nih.gov/pubmed/31583122 http://dx.doi.org/10.1038/s41420-019-0218-y |
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