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Differential regulation of OCT4 targets facilitates reacquisition of pluripotency

Ectopic transcription factor expression enables reprogramming of somatic cells to pluripotency, albeit with generally low efficiency. Despite steady progress in the field, the exact molecular mechanisms that coordinate this remarkable transition still remain largely elusive. To better characterize t...

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Detalles Bibliográficos
Autores principales: Thakurela, Sudhir, Sindhu, Camille, Yurkovsky, Evgeny, Riemenschneider, Christina, Smith, Zachary D., Nachman, Iftach, Meissner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768871/
https://www.ncbi.nlm.nih.gov/pubmed/31570708
http://dx.doi.org/10.1038/s41467-019-11741-5