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Differential regulation of OCT4 targets facilitates reacquisition of pluripotency
Ectopic transcription factor expression enables reprogramming of somatic cells to pluripotency, albeit with generally low efficiency. Despite steady progress in the field, the exact molecular mechanisms that coordinate this remarkable transition still remain largely elusive. To better characterize t...
Autores principales: | Thakurela, Sudhir, Sindhu, Camille, Yurkovsky, Evgeny, Riemenschneider, Christina, Smith, Zachary D., Nachman, Iftach, Meissner, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768871/ https://www.ncbi.nlm.nih.gov/pubmed/31570708 http://dx.doi.org/10.1038/s41467-019-11741-5 |
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