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Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer

The Newcastle disease virus (NDV) strain AF2240 is an avian avulavirus that has been demonstrated to possess oncolytic activity against cancer cells. However, to illicit a greater anti-cancer immune response, it is believed that the incorporation of immunostimulatory genes such as IL12 into a recomb...

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Detalles Bibliográficos
Autores principales: Mohamed Amin, Zahiah, Che Ani, Muhamad Alhapis, Tan, Sheau Wei, Yeap, Swee Keong, Alitheen, Noorjahan Banu, Syed Najmuddin, Syed Umar Faruq, Kalyanasundram, Jeevanathan, Chan, Soon Choy, Veerakumarasivam, Abhi, Chia, Suet Lin, Yusoff, Khatijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768883/
https://www.ncbi.nlm.nih.gov/pubmed/31570732
http://dx.doi.org/10.1038/s41598-019-50222-z