Pharmacokinetics of thiotepa in high-dose regimens for autologous hematopoietic stem cell transplant in Japanese patients with pediatric tumors or adult lymphoma

PURPOSE: Thiotepa is used in high-dose chemotherapy (HDT) before autologous hematopoietic stem cell transplantation (HSCT) to treat solid tumors and hematological malignancies. This Phase 1 study was conducted to establish the pharmacokinetics (PK) of thiotepa in a Japanese population. METHODS: HDT/...

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Detalles Bibliográficos
Autores principales: Kondo, Eisei, Ikeda, Takashi, Goto, Hiroaki, Nishikori, Momoko, Maeda, Naoko, Matsumoto, Kimikazu, Kitagawa, Hideo, Noda, Naoto, Sugimoto, Saori, Hara, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768914/
https://www.ncbi.nlm.nih.gov/pubmed/31428821
http://dx.doi.org/10.1007/s00280-019-03914-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768914/
https://www.ncbi.nlm.nih.gov/pubmed/31428821
http://dx.doi.org/10.1007/s00280-019-03914-2

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