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Destruction of tumor mass by gadolinium-loaded nanoparticles irradiated with monochromatic X-rays: Implications for the Auger therapy

Synchrotron generated monochromatic X-rays can be precisely tuned to the K-shell energy of high Z materials resulting in the release of the Auger electrons. In this work, we have employed this mechanism to destruct tumor spheroids. We first loaded gadolinium onto the surface of mesoporous silica nan...

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Detalles Bibliográficos
Autores principales: Matsumoto, Kotaro, Saitoh, Hiroyuki, Doan, Tan Le Hoang, Shiro, Ayumi, Nakai, Keigo, Komatsu, Aoi, Tsujimoto, Masahiko, Yasuda, Ryo, Kawachi, Tetsuya, Tajima, Toshiki, Tamanoi, Fuyuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768997/
https://www.ncbi.nlm.nih.gov/pubmed/31570738
http://dx.doi.org/10.1038/s41598-019-49978-1