Stromal cells downregulate miR-23a-5p to activate protective autophagy in acute myeloid leukemia

Complex molecular cross talk between stromal cells and the leukemic cells in bone marrow is known to contribute significantly towards drug-resistance. Here, we have identified the molecular events that lead to stromal cells mediated therapy-resistance in acute myeloid leukemia (AML). Our work demons...

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Detalles Bibliográficos
Autores principales: Ganesan, Saravanan, Palani, Hamenth Kumar, Lakshmanan, Vairavan, Balasundaram, Nithya, Alex, Ansu Abu, David, Sachin, Venkatraman, Arvind, Korula, Anu, George, Biju, Balasubramanian, Poonkuzhali, Palakodeti, Dasaradhi, Vyas, Neha, Mathews, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769009/
https://www.ncbi.nlm.nih.gov/pubmed/31570693
http://dx.doi.org/10.1038/s41419-019-1964-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769009/
https://www.ncbi.nlm.nih.gov/pubmed/31570693
http://dx.doi.org/10.1038/s41419-019-1964-8

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