An anti-CD103 antibody-drug conjugate prolongs the survival of pancreatic islet allografts in mice

CD103 mediates T-cell infiltration and organ allograft rejection, and depletion of CD103-expressing cells is a promising therapeutic strategy for allograft intolerance. Recently, we verified that M290-MC-MMAF, an anti-CD103 antibody-drug conjugate, potently eliminates CD103-positive cells in vivo, w...

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Detalles Bibliográficos
Autores principales: Xue, Da, Liu, Pili, Chen, Wangming, Zhang, Chi, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769010/
https://www.ncbi.nlm.nih.gov/pubmed/31570722
http://dx.doi.org/10.1038/s41419-019-1980-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769010/
https://www.ncbi.nlm.nih.gov/pubmed/31570722
http://dx.doi.org/10.1038/s41419-019-1980-8

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