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BCR-ABL Independent Mechanisms of Resistance in Chronic Myeloid Leukemia

Not all chronic myeloid leukemia (CML) patients are cured with tyrosine kinase inhibitors (TKIs), and a proportion of them develop resistance. Recently, continuous BCR-ABL gene expression has been found in resistant cells with undetectable BCR-ABL protein expression, indicating that resistance may o...

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Detalles Bibliográficos
Autores principales: Loscocco, Federica, Visani, Giuseppe, Galimberti, Sara, Curti, Antonio, Isidori, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769066/
https://www.ncbi.nlm.nih.gov/pubmed/31612105
http://dx.doi.org/10.3389/fonc.2019.00939