Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer’s Disease

Myeloperoxidase (MPO) is an enzyme expressed mostly by neutrophils and is a primary mediator of neutrophils oxidative stress response. While a profound body of evidence associates neutrophil-derived MPO in the pathogenesis of Alzheimer’s disease (AD), this role has not been assessed in an animal mod...

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Detalles Bibliográficos
Autores principales: Volkman, Rotem, Ben-Zur, Tali, Kahana, Anat, Garty, Ben Zion, Offen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769081/
https://www.ncbi.nlm.nih.gov/pubmed/31611761
http://dx.doi.org/10.3389/fnins.2019.00990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769081/
https://www.ncbi.nlm.nih.gov/pubmed/31611761
http://dx.doi.org/10.3389/fnins.2019.00990

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