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Systematic Profiling of Alternative mRNA Splicing Signature for Predicting Glioblastoma Prognosis

Emerging evidence suggests that alternative splicing (AS) is modified in cancer and is associated with cancer progression. Systematic analysis of AS signature in glioblastoma (GBM) is lacking and is greatly needed. We profiled genome-wide AS events in 498 GBM patients in TCGA using RNA-seq data, and...

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Detalles Bibliográficos
Autores principales: Chen, Xueran, Zhao, Chenggang, Guo, Bing, Zhao, Zhiyang, Wang, Hongzhi, Fang, Zhiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769083/
https://www.ncbi.nlm.nih.gov/pubmed/31608231
http://dx.doi.org/10.3389/fonc.2019.00928