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FKBP12 is a predictive biomarker for efficacy of anthracycline-based chemotherapy in breast cancer

BACKGROUND: FK506-binding protein 12 (FKBP12) is abundant, ubiquitously expressed cytoplasmic protein with multiple functions in cell signaling transduction. Recently, we reported a novel function for FKBP12 in oncoprotein mouse double minute 2 (MDM2) self-ubiquitination and degradation, which great...

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Detalles Bibliográficos
Autores principales: Xing, Mingyou, Wang, Jun, Yang, Qin, Wang, Yu, Li, Jiansha, Xiong, Jing, Zhou, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769097/
https://www.ncbi.nlm.nih.gov/pubmed/31428819
http://dx.doi.org/10.1007/s00280-019-03923-1